She married the American actor Ian Gomez in September 1995. Gomez converted to Greek Orthodoxy prior to marrying her. She became a U. S. citizen in 1999. In 2008, they adopted a daughter and named her Ilaria. Vardalos posted an advice column about the adoption process in The Huffington Post. It was announced on July 3, 2018, that Vardalos had filed for divorce from Gomez after 23 years of marriage and that they had already been separated since June 2017 because their relationship had turned into a friendship.